As discussed in the assay
performed to test the inhibition of superoxide production by glabridin, it can be said
that glabridin has an antioxidant effect in addition to its skin-whitening
(anti-melanogenetic) and anti-inflammatory properties.
Licorice used topically is
documented to reduce the amount of corticosteroids in dermatological infections. This is
probably by inhibiting 11 - beta hydroxysteroid dehydrogenase which is responsible for the
conversion of cortisol to corticosterone and thus, potentiating the effects of steroids.